The American Chamber of Commerce in Moldova (AmCham Moldova) is a non-government non-profit organization, founded on September 4, 2006. As a member of the international network of 112 AmChams from the 99 countries worldwide, AmCham Moldova connects businesses and business leaders to share the common goal of bringing the entrepreneurial spirit and cultures of Moldova and the United States closer together.

AmCham Moldova's membership, currently encountering 70 members, is composed of a diverse spectrum of businesses, from large investors to small goods and service providers that operate within Moldova, as well as Moldovan companies of all sizes that are pursuing trade with the United States.